VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Pangolin

Scientific Name: Manis javanica

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Pholidota-> Manidae-> Manis

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Enterovirus A71

Family: Picornaviridae

Receptor: SCARB2

Receptor SCARB2 information

Summary: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_0035 2021.04 10X Genomics Duodenum Normal 1482 Link
Vthunter_0036 2021.04 10X Genomics Esophagus Normal 24581 Link
Vthunter_0037 2021.04 10X Genomics Heart Normal 12958 Link
Vthunter_0038 2021.04 10X Genomics Kidney Normal 4481 Link
Vthunter_0039 2021.04 10X Genomics LargeIntestine Normal 3328 Link
Vthunter_0040 2021.04 10X Genomics Liver Normal 5694 Link
Vthunter_0041 2021.04 10X Genomics Lung Normal 13720 Link
Vthunter_0042 2021.04 10X Genomics Spleen Normal 3207 Link
Vthunter_0043 2021.04 10X Genomics Stomach Normal 12485 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of SCARB2 in human tissues   [NCBI]

Expression: Ubiquitous expression in brain (RPKM 74.6), prostate (RPKM 71.6) and 25 other tissues

Protein expression of SCARB2 in human tissues   [Proteinatlas]